|
| |||||||||||
| |||||||||||
Full Screen- Title
- Declaration
- Certificate
- Dedication
- Acknowledgement
- Contents
- Abstract
- Preface
- List of Figures
- List of Tables
- Abbreviations
- 1. Introduction and review of literature
- 1.1. Oxidative stress
- 1.2. Sources of ROS (Reactive Oxygen Species)
- 1.3. Consequences of oxidative stress in biological system
- 1.3.1. Lipid peroxidation and lipid hydroperoxide formation
- 1.3.2. Oxidative DNA damage
- 1.3.3. Mitochondrial damage
- 1.3.4. Damage to Proteins
- 1.4. Oxidative stress and diseases
- 1.4.1. Carcinogenesis and cancer
- 1.4.2. Inflammation
- 1.4.3. Cardiovascular disease and renal dysfunction
- 1.5. Drug induced oxidative stress
- 1.5.1. Hepatotoxicity
- 1.5.1.1. Acetaminophen-induced Hepatotoxicity
- 1.5.2. Carditotoxicity
- 1.5.3. Nephrotoxicity
- 1.6. Radiation induced oxidative stress and its effects on biological system
- 1.7. Antioxidant defence mechanisms of the cell against oxidative stress
- 1.8. Mitigation of drug and radiation induced oxidative stress by extracts and phytoceuticals from medicinal plants
- 2. Materials and Methods
- 3. Free radical scavenging and antiinflammatory activities of the extracts of medicinal plants -A.Calamus, H.Indicus and C.Fenestratum and αlpha-Asarone
- 4. Studies on anti-tumor activity of C.Fenestratum extract
- 5. Protection of membrane lipids and cellular DNA against γ-radiation induced damages by the extracts of medicinal plants - A.Calamus and H.Indicus and αlpha-Asarone
- 6. studies on the tissue protective efficacy of the extracts of medicinal plants - A.Calamus and H.Indicus and αlpha-Asarone against whole body exposure of mice to γ-radiation
- 7. Enhancement in repair of radiationinduced DNA strand breaks by the extracts of medicinal plants - A.Calamus and H.Indicus and αlpha-Asarone
- 8. Effect of A.Calamus extract and αlpha-Asarone on radiation induced micronuclei formation and chromosomal aberration
- 9. Amelioration of acetaminophen induced hepatotoxicity in mice by A.Calamus extract and αlpha-Asarone
- 10. Protective effect of A.Calamus extract and αlpha-Asarone against doxorubicin induced myocardial toxicity
- 11. Aamelioration of Cisplatin-induced nephro-toxicity by A.Calamus extract and αlpha-Asarone
- Summary and Conclusion
- Bibliography